How is it possible that a substance like THC has almost
no effect on small children?
Caring
for a sick child is a lot like carrying the unbearable weight of a giant
boulder uphill even though the child often weighs less than a small stone. In
my experience there is a difference between adult suffering and child suffering
in terms of how each handles their pain and sorrow in sickness. And ii have
noticed that little children are much better at dealing with sufferance and ii
am convinced that this has a lot to do with receptor expression. Some
scientists now accept that the role of the EC system begins at conception and
continues throughout pregnancy and beyond to ensure overall optimal health of
the living human being.
Professor
Ester Fride Ph.D. passed away 1 January 2010 age 56. She was the Dutch born
Israeli scientist who worked with Professor Mechoulam in the 1990’s and became
known for revealing the fact that a new born mammal cannot suckle and survive
without a functional EC system. She worked closely with Professor Mechoulam and
the two shared a lab. He graced her with the title of Chairperson at the Department of
Behavioural Sciences and the Department of
Molecular Biology at The College of Judea
and Samaria in Ariel Israel. In 2000 she was given her own lab and began
researching the role of the EC system in the infant suckling process.
Thanks
to her research we now have scientific proof that the activation of our
Cannabinoid receptors by our natural Endocannabinoids is crucial to the
suckling response in new born babies. She co-authored over 40 research papers
where she released research which suggested a very promising future for the
study of Cannabinoids in paediatric medicine. It was Professor Fride’s research
going back to 2004 which proved that our own Endocannabinoids were naturally
present in human breast milk and that Cannabinoids are necessary to stimulate
the suckling process in new born mammals. Part of this research also revealed
that Endocannabinoids help to stimulate the tongue muscles and this is why
today we remain confident in going forward and treating various swallowing
difficulties with Cannabis medicine in adults and children because the research
results are so successful.
Professor
Ester referred to Endocannabinoids as “extremely vital for proper human
development” and some of her later work revealed that
Endocannabinoids play a major role in the development of the foetal brain and
she also discovered that Endocannabinoids can be altered when a pregnant mother
is under stress regardless of whether the mother consumes Cannabis or not. From
the very first feed a human baby is offered from its mothers breast a new born
human is already experiencing an activation of its EC system which is the start
of building its own immune system and other physiological systems in the body.
Possibly of greatest importance is that Professor Fride’s work proved that in
infants growth failure due to the inability to take up food was attributed to
an under developed EC system. Once the baby starts suckling, the Anandamide and
2-AG from the maternal milk automatically increases these levels in the brain
which in turn stimulates feeding.
Professor
Ester’s theory proves that blockages of Cannabinoid receptors contribute to
infant failure to thrive conditions
because of the failure to stimulate the suckling response in infants. This is
one of the reasons she strongly advocated the use of Cannabinoids in paediatric
practise.
Every
new day we hear positive stories of what Cannabis can do for children
especially in respect of many types of cancers, epilepsy, autism for example.
It was Professor Fride’s studies which also revealed that our natural THC,
Anandamide displayed a neuro-protective role on the post-natal brain. The fact
that our Cannabis receptors are present in the white matter regions of the pre
and post-natal nervous system proves that the EC system plays a specific role
in early brain development. Throughout our lives from conception to end of life
THC is required to ensure healthy human brain development and this is why we
need the Cannabis plant in our daily lives.
How is it possible that a substance
like THC has almost no effect on small children?
Professor
Fride’s work proved that Cannabinoid receptors develop very slowly during the
post-natal stage. This ties up with observations that small children appear to
be insensitive to the psychoactive effects of controlled Cannabinoid treatment
and specifically to THC. Because of Professor Fride’s revelation we now know
that this gradual increase of EC system activity in the human body is also
accompanied by a gradual maturation in the response to the psychoactive
properties of THC. In studies of post-natal mice a gradual increase in the
density of THC receptors was recorded in the brain and this led to the
important discovery that small children can benefit from Cannabis medicine
without any harsh side effects. My personal research has brought up numerous
studies from Hebrew
University in Israel where children between the ages of 3 and 13
undergoing chemotherapy were administered high THC doses, approximately 0.64
mg/kg per treatment. Some of these children were given doses for long periods
of time up to 114 treatments based on 4 treatments per 24 hour period. The
anti-emetic effects were also impressive with no real side effects at all. And
in another of her studies eight children between the ages of 3 and 14 years
with severe neurological damage were treated with between 0.04 – 0.12 mg/kg per
day. Across the board improvements in behaviour included reduced
spasticity, improved dystonia (muscle movements), increased interest in
surroundings and anti-epileptic activity, all with no notable side effects.
This same study included the case of an 11 year old girl who after a motor
accident suffered a spinal contusion with total paraplegia and a frontal skull
fracture. The patient suffered from posttraumatic stress disorder, mood
disturbances and lack of appetite. The daily THC dose administered improved her
appetite and mood as well as her spasticity with no side effects.
Over
the past twenty years we have seen really excellent clinical results of
Cannabis treatment in small children and young adults especially in paediatric
oncology cases and where children have been suffering with serious neurological
conditions and brain trauma such as epilepsy. All of these healings become
possible because of the now scientifically proven fact that Cannabinoid
receptor expression is different in children.
It
is interesting to note that only a temporary presence of receptors are
expressed during development but not during adulthood in certain regions of the
brain at the Corpus Callosum and the anterior commissure which connects the
neuronal pathways between the left and right hemispheres of the brain. These
expressions were noted between gestational day 21 and post-natal day 5 and this
proves the important role for Cannabinoids in human brain development. This
natural paediatric expression of the human EC system is in my mind so clearly
and so obviously designed to be a biologically adaptive defence mechanism
designed to protect children from illness because children are not supposed to
be ill.
What about Human studies?
In
her human studies Professor Ester confirmed the results of past mice studies
and Cannabinoid receptors were identified in the human embryo at week 14 of
gestation. In the 20th week of gestation in the human embryo a
selective (lesser) expression of the receptors was identified in the
hippocampus compared with a much wider expression in the adult human brain. An
advanced increase in the concentration of these Cannabinoid receptors was found
in the frontal cortex, hippocampus, basal ganglia and cerebellum between the foetal
period and adulthood.
This
proves that these receptors are functionally active at all stages of human
development. So in other words the receptor concentration in these parts of the
brain increased progressively only as the human progressed and grew. We can
clearly see how nature has accommodated small children by ensuring only
progressive development of the highly evolved EC system. The most important
finding was that the psychoactive effects of Cannabinoid treatment is virtually
absent or extremely reduced in children (in controlled studies) and now we know
that this is because of the lower concentrations of the actual receptors at
younger ages.
Is Cannabis the Human Vaccination Plant?
It
is my personal belief that Professor Fride’s work was leading towards revealing
the truth that Cannabis can very well replace vaccinations in small children.
This is a controversial topic especially as certain vaccinations are blamed for
the probable cause of many neurological disorders manifesting in small children
such as ADD (Attention deficit disorder), ADDH (Attention deficit disorder with
hyperactivity), epilepsy, autism and so many other related conditions. And the
fact that Cannabis is already being investigated as potential healing solutions
for most of these conditions is more evidence in the case of this plant taking
on the absolute character of being our true human companion plant starting from
the point of our conception. The truth is that when you vaccinate a child you
not only activate the immune system you also turn on the brains’ immune system.
The reality is through vaccination the immune reaction goes on for years,
non-stop, resulting in an inflamed brain that will not calm down and this is
what contributes to brain dysfunction in small children after being vaccinated.
It
is also shocking to learn that most vaccinations contain MSG, mercury,
aluminium, nagalase and other dangerous metals all which we know can cause
serious neurological damage. And ii know of many Jewish and Muslim families who
do not vaccinate because there is pig product in the gelatine used in
vaccination drugs. It’s interesting when reading doctors’ reports where they
use descriptions like ‘the patient’s brain was on fire’ and
ii always wonder how do they know that this is what it feels like to have an
inflamed brain? The only reason they could know this is because trial
tests were actually performed and they know that this is a side effect of these
vaccinations explaining the strong connection between autism and vaccinations.
The truth is that if we were to find natural cures for health issues this would
result in less profits for the pharmaceutical and related industries. And sadly
a lot of false evidence is presented to the medical field especially to child
psychiatrists and paediatricians.
Scientists
seem to have this type of power to guarantee the products of large corporations
in exchange for financial rewards. The supporters of vaccinations simply state
that they are safe without any evidence at all and we all just have to accept
it without asking questions about safety. They make false statements that
mercury is safe and increases the IQ, and we must just accept this as truth
when in reality it is lies and the complete opposite is truth. So a lot of
doctors are intentionally misled about the safety of some of these drugs which
are actually toxic. But the minute people stand up and suggest that excessive
vaccination can increase the risk of not only autism, but also schizophrenia
and other neurodegenerative disorders then they are the ones screaming for
evidence.
And
despite inundating them with thousands of studies they always proclaim that
such studies are insufficient or unacceptable. Mostly they just ignore the
evidence. Most of the evidence presented to governments include cell culture
studies, mixed cell cultures, organotypic tissue studies, in vivo animal
studies using multiple species and even human studies. So for the wardens of
vaccine safety the evidence provided by the opponents is never accepted and
probably never will be.
It
is through Professor Fride’s work that we now know how Cannabis affects
children from the unborn baby to postnatal development and beyond to adulthood
and so ii would like doctors, nurses, parents, grandparents and caregivers to
feel a little more comfortable in knowing that we are not harming our children
and come closer to accepting that Cannabis is quite possibly a medicine intended
to cure all childhood illnesses. It is because we all have natural dedicated
Cannabinoid receptors regulating our nervous and immune systems throughout
human life that ii am convinced that the Cannabis plant will also become known
as The Human Vaccination Plant.
Cannabis
is a powerful pain killer and anti-inflammatory and this is the first plant
property required by babies suffering the harsh side effects of vaccinations.
In my research ii have seen thousands of babies benefit from the pain relief
which Cannabis medicine can offer. Vaccinations undoubtedly set the immune
system and the brain on fire and Cannabis medicine is exactly the type of
relief moms need the next few nights after vaccination day. In Cannabis we
have a natural medicine which helps to reduce, treat and manage any side
effects which do result from vaccinations including autism, encephalitis,
seizures, fever, anxiety, irritability, nausea, vomiting and all the other
horrible things that are associated with vaccinations. They always say that
more research is needed but the truth is that Cannabis is the most researched
plant and there is by far more research on Cannabis medicine than there is
available on any pharmaceutical drug.
In
a 1982 research study by Medical Assistant Katherine
Tennes 756 pregnant moms were studied and 34% consumed Cannabis. This study
found NO developmental difference in infants of moms who consumed Cannabis
during pregnancy and breastfeeding. So Cannabis really has presented itself to
be the most impressive immune stimulator specifically designed to work via our
highly advanced receptor system. Oh! Did ii mention that Cannabis babies sleep
much better? Happy baby happy mom!