Safety Concerns and Potential Side-Effects of Cannabis Medicine

 

Today I am going to speak about some of the safety concerns and potential side-effects of Cannabis Medicine. Please note that I am speaking about full spectrum organic whole plant medicine and not the synthetic cannabinoid products that are up to 800 times stronger than plant medicine and have serious side-effects, fatalities and product recalls.

The truth is that the Cannabis plant is one of the safest plant medicines available today when correctly prescribed … BUT… in today’s post-modernist society I am here to tell you that it is NO LONGER safe to self-medicate with this medicine whether you are using medicinally or recreationally.

It is absolutely imperative that anyone who is wondering whether Cannabis could help them or a loved one, must please consult with someone who has studied the Endocannabinoid System (ECS) and knows how to prescribe this medicine.

The reason why human beings need THC is because it is only the THC molecule that can bind to the ECS receptors to activate the system BUT,,, only teenzy weenzy amounts are required to achieve this. And THC is ONLY found in the Cannabis plant.

So even though this plant is now scientifically implicated in 678 medical conditions including sars virus and Alzeheimers…Medical Doctors are still not being taught about the ECS at medical schools. Fortunately today there are many online courses that offer CPD points to clinicians to encourage them to study the system so that they can confidently advise their patients about dosing and delivery routes.

And when purchasing any Cannabis medicine please insist on a COA, this is the only real way that you can truly know what is actually inside the thousands of products that have popped onto the shelves since 2018.

Doctors and healers need to be aware of what the medical world refers to as the biphasic effect of medicine.

This medical rule is not unique to Cannabis medicine it is a general medical principle that means that high and low doses can have opposite effects. A good example is alcohol, where at first a person seems “stimulated” but after one too many the same person can become sedated…and the same thing can happen with Cannabis Medicine, antibiotics, blood pressure meds and many others, contraception is also a bi and tri-phasic medicine where different effects are experienced at different doses.

Remember that in the 1980’s and early 90’s even, 6% THC was considered high and today we have “over 30’s” clubs, and the average THC readings are around 22% this is more than 3 x stronger than many people are able to cope with, especially Cannabis naïve patients and the elderly

So for example a person who has been using Cannabis for anxiety may now start finding that they are experiencing anxiety instead of calming it, this is because of the biphasic effect where a high THC dose is having the opposite effect. So it is incredibly important to be aware of this and my advice is to seek out strains that do not exceed 15% THC and that is quite high already.

In simple terms today’s high THC strains that contain no CBD are far too strong for most medicinal use. In my book I explain how current breeding practices could ultimately end up out-breeding CBD. Truly I feel that the greatest threat to the plant’s safety margin is man’s quest for the highest THC strains.

Healers and doctors also need to be aware that the ECS controls the human hormone system and in certain types of hormonal cancers one has to be precise with dosing so as to avoid the biphasic effect in respect of THC.

In other words, if your doctor or healer prescribes too high CBD or THC in certain hormonal cancers you could end up feeding the cancer instead of destroying it….I cannot stress the importance of this statement enough…..because most definitely Cannabis does destroy most types of cancer in a number of ways, but the truth is that only minute amounts of THC is required in the presence of the other plant molecules.

Always ask your grower or your healer what the CBD percentage and terpene profile is of your flowers and your oils or tinctures. Very important to ask questions to make informed opinions about your health and happiness.

It is also very important that the person selling you any medical product must do the “Drug to Drug Interaction Checks” for CBD and THC.

I have spent many years helping people to work out dosage on products I did not produce and I see this as a huge concern going forward,  and I urge everyone to ask the oil maker directly what is in the medicine you have bought and always insist on COA.

This is so important… I again cannot stress this enough especially for patients using statins, heart meds, blood pressure meds and blood thinners but also most chronic medications, there are a lot of pharmaceutical interactions that must be considered before administering Cannabinoid Medicine and not everyone today is a candidate for this treatment, largely due to Drug Interactions.

The best strains for the least side effects are the 1:1 strains where the plants have the same % CBD as THC. Doctors I have worked with absolutely love these strains for making medicine because there are hardly any side-effects because of the presence of CBD.

I’m sure by now many people have heard about the “Entourage Effect”…. that means that all of the plants chemicals must be present in order for the medicine to be safe and effective. There are more than 160 cannabinoids and more than 200 terpenes in this plant that offer protection to humans and animals, but these must be present in the plants that are used to make medicine.

My Two Top medical concerns today are adolescent use and pre-existing and undiagnosed mental health conditions.

The truth is that you cannot die from dagga in the same way as alcohol can kill you. According to the WHO Cannabis has a very low addiction rate at 3% where coffee is at 7%, alcohol at 10.2% and tobacco at 30%

We know that in children, under 12 years old there is a biologically built-in defense mechanism known as “Delayed Receptor Expression” that protects small children from the psychoactive effects THC.

You can find my talk on Child Safety on my rumble account where I unpacked 14 scientific facts as evidence to safety of THC in small children.

This means that children over 12 years old are becoming receptive to the effects of THC, and special medical considerations are required in terms of dosing and application when the adolescent might need treatment that targets the ECS. For example refractory epilepsy, asthma and cancer in teenagers.

My biggest concern with teenagers is high THC and the biphasic effect that can lead to psychosis.

In my experience, and there is a lot of scientific evidence that the majority of patients, including young people, with psychosis, suffered with it before they consumed Cannabis. Please know that I absolutely do not condone self-medicating any medicine but especially Cannabis because of today’s high THC strains.

Anyone with pre existing or undiagnosed mental health conditions must stay far away from high THC and seek out plants that are between 6 to 12% THC never higher than 15%. I cannot stress this enough.

The big question is still…. Does dagga damage brain cells????

One of the main functions of THC and the ECS, is neurogenesis, the creation of new brain cells, and many doctors today have witnessed what this plant can do for the human brain especially in children suffering with seizures, spasms and other brain traumas. Most gliomas aka brain tumors respond exceptionally well to properly prescribed THC. Today there is absolutely zero scientific evidence to prove that this plant in any way damages brain cells.

There is a very good biological reason why it is impossible to overdose on this plant

There are ECS receptors on every single cell in the human body EXCEPT for 2 types of cells….. the Cardiac and Respiratory cells in the Medulla Oblongata.

This means that a human being or animal cannot die from a heart attack or stop breathing from consuming Cannabis, and this is  the biological reason why no human being has ever died from plant Cannabis Medicine.

When it comes to plant safety there are a number of reasons for the high safety margin of this plant

It is a scientific fact that Plant THC only acts a partial agonist at the ECS receptors and that CBD naturally calms the effects of THC.

Compared  to synthetic THC products that act as FULL agonists and this is the reason why man-made synthetic and single molecule Cannabis medicine is 800 x stronger and have severe side effects.

You can read all about plant safety in my book but let me explain exactly how CBD mitigates the effects of THC inside the human brain. This is an extract from my clinical practice book.

KEY TAKE-AWAY POINTS:

• CBD can bind to many receptors in the body but it cannot actually bind to the ECS receptors.

• It does however interact with the ECS and there are even CBD ‘docking bays’ on most of cells in the body.

• CBD acts as an antagoninst at the ECS receptors

• CBD can alter the shape of the ECS receptors

Scientists refer to this as “negative allosteric modulation of CB1 & 2 receptors”. The secret is that CBD can actually change the shape of the Cannabis receptors. This, in turn, affects the potency and reduces the effects of THC as it binds with the receptor. [15] (Pertwee, 2008)

Imagine that the surface of the receptor is more or less the same shape as a blood cell like a disc shaped doughnut with a hole in the middle. This hole represents the THC docking bay that requires the THC molecule in order to activate the system and open the receptors.

CBD has the ability to alter the shape of our receptors from a round donut to resemble, say, a sickle or half- moon shape. This then reduces the surface area of the receptor by half and by reducing the surface area of the receptor this reduces the THC uptake, and in turn minimizes the psychedelic effects of the THC (Marzo,et al 2014) [17] (W Jaeger, 2008)

Today, smoking the plant is the least popular way of medicating. We now have so many different products to try but one of the best ways of consuming this plant is in its raw form.

And this is another great way to avoid THC without losing the benefits, because the truth is that there is hardly any THC in the raw plant because the chemicals are still in their “acid versions” and chemically they then have an ‘A’ behind their letters so THC within the raw plant is known as THCA and CBD is CBDA and so on for all the different Phytocannabinoids. The plant terpenes also play a vital role in healing and it is now known that all terpenes are cannabimetic meaning that they have the same healing properties as the cannabinoids. 

There is an amazing study of the cannabinoid acids in the field of Migraines and Nausea where CBDA was 1000 times stronger than CBD and in that same study THCA was 25% stronger than THC.

People are literally healing themselves from cancer by adding raw cannabis plant to their smoothies and I encourage everyone to do this as a preventative measure, like a daily supplement, so that in times of illness your Endocannabinoid System will be able to defend you.

Endocannabinoid Deficiency is now a recognized medical condition and I have seen in my life how so many doctors miss this therapeutic target that can assist humans and animals with 678 medical conditions. That is really something!

In my practice I work with ultra low dosing and the idea is to never let my patients develop a tolerance to THC

As a rule of thumb ….as THC levels increase, dosage should decrease because only minute amounts of THC in the presence of CBD and other plant molecules, is all that is needed to treat most diseases and ailments with zero side-effects.

As mentioned before the only way to assess potency and purity of plant material is to insist on a Certificate of Analysis from a reputable laboratory.

You must always look at the ratios of THC to CBD, A higher ratio of CBD to THC typically means less psycho activity and therefore a lower risk of any side effects. I work on a 15 to 1 ratio in my practice for common ailments like anxiety, depression, insomnia, pain, inflammation, skin conditions and chemo care.

Cannabis is unlike any other medicine we know or have studied before and the truth is that only very low doses are needed to nudge the ECS in the right direction and for your body to start producing enough Endocannabinoids and ECS receptors to start healing.

I have witnessed how often patients on lower doses experience more significant symptom relief, especially for pain and sleep conditions.

And often times when a patient does not achieve efficacy the treatment is actually enhanced by REDUCING the dose instead of increasing the dose and this is very interesting medical response in the majority of people who try ultra low dosing protocols.

So the big question is : “Is Cannabis the be-all and end-all of modern medicine?”

The simple answer is of course NO!

There really are no magical ‘cure-all’ remedies and no one should expect this from the Cannabis plant as there are so many variants at play in disease assessment today especially the uniqueness of the individual ECS.

This is why I urge people to not wait until they or their loved ones are already at the end before thinking about inviting Cannabis into your lives. My whole life people have been coming to me on their deathbeds after the doctor has sent them home and I have seen hundreds if not thousands of stage 4 recoveries In my life, but unfortunately sometimes it is simply too late.

It is never fair to offer false hope but the truth is that for the majority of people who have tried Cannabis, the plant has offered them healing in one way or another.

So my message to everyone today is to be super conscious of Responsible Adult Consumption of THC, as well as harm reduction in our communities.

All Cannabis shops, dispensaries and social clubs have a huge role to play in Harm reduction today and I would love to urge owners of these establishments and anyone thinking of opening a Cannabis business to educate themselves and their staff on the medical aspects of the plant and to be conscious of members who might have pre existing or undiagnosed mental health conditions.

A big part of this social responsibility is to also offer members low THC and 1:1 strains that contain more CBD. It is always a good idea to have pre-rolled CBD flower on offer as well as a high CBD tincture in your first aid kit

Unfortunately today due to politics and economic greed surrounding this plant, one can no longer trust the scientific research online even on Pubmed. There have been recent court cases earlier this year that prove that 94% of funded Cannabis Medicine research is geared to finding harm with the plant. This means that only 6% of funded research is geared to positive outcomes, so you actually have to find someone who knows what they are talking about.

Here in South Africa there is no shortage of Doctors and Healers who have studied the ECS and if anyone needs any help please feel free to contact me directly and I will refer you to a practitioner in your area or assist you myself.

 

Redefining Narcissism, Trauma and the Ego

It really pains me to see so many people hating on certain so-called segments of our society.....yes, sure, psychologists claim that 1 in 4 are narcissistic....let me tell you the truth that ii see, that is each one of us has the ability to show these tendencies....because we are all in pain....we are ALL traumatized in one way or another....whether we know it or not.

And yes absolutely it is each one of our responsibility to ensure that our triggers and fears do not ruin other people in the process....but not everyone has the strength to actually do this.

People who are in daily pain are weak people who do not have the strength to help themselves and therefore they need help to cope with their emotions, thoughts and actions. 

Being in a relationship with a known narcissist is an incredibly painful challenge and ii urge couples to address these type of concerns long before the church bells start ringing.

In my opinion, those of us who enjoy gossiping and speculating about so-called narcissists are in fact also narcissists, myself included, because this type of behaviour also stems from the place of ego because the ego thrives on comparison and this is an easy trap for all of us to fall into.

The Ego is not something to drop, it is not something to destroy, you yourself are that ego…and all the egos are little building blocks of this world

There’s no shortage of new age dogma that teaches us about this so-called 5^th dimension. This doctrine also teaches that humanity must lose the ego. I’v met so-called teachers of the 5^th dimensional transcendence process and they claim to be egoless, yet their lives are not reflecting anything to convince me that this dogma is actually working for them. In my opinion to ‘lose the ego’ is to lose consciousness! We must become more concerned about the collective ego and the collective consciousness and less concerned about destruction and separation and division, it’s all about wholeness.

They claim to be superior beings moving to a superior 5D world. The truth is that if you really study these topics you will know that the so-called 5^th dimension is actually so tiny and right now it is actually stuck between 4 and 6 like it is pinched between those two dimensions.

Personally I recommend the 6h dimension there is far more love to be found there but there is also a lot of karma there.

So in my opinion no one is superior and no dimension is superior and in my studies my late teacher used to always send me to the 13^th dimension and that is where all the action is. Up there we no longer have a digestive tract, every spirit up there is a breatharian! And with no gut there is no disease, toxicity and no psychosis!

We must question everything and avoid falling into spiritual traps that promote negativity like separation, selfishness and self-hatred. I also question the mentality that these so-called superior people will simply leave us plebs behind and move on….that does not sound very irie to me, quite cold actually!

If you wish to travel spiritually I urge people to not fall prey to the many false life teachings that have deceived us for eons. (All of these studies will be shared in my upcoming book The Secret Place of The Most High)

The truth is and we must realize that we are that ego that these teachers are suggesting you must destroy. So this is actually where self-hatred comes from and another truth is that whatever we reject or deny, will ultimately possess us, that is a fact and the true teaching is “What we resist will persist”. To destroy the ego would mean to destroy yourself and you should ask yourself why would you want to become entrapped in such a teaching? Perhaps we should consider simply surrendering to our own egos. The goal is to be authentically human. 

"Before Enlightenment; chop wood, carry water. After Enlightenment; chop wood, carry water." (Zen Koan)

In my opinion people who present or identify as "Echoists" aka empaths, are really just subliminal narcissists because we are simply suppressing our own personalities because of our past trauma. These people believe that other people’s happiness and needs come before theirs and this they believe to be a requirement in order to find love and approval. 

Like narcissists, the opposite end of the scale also display poor mental health and end up in dysfunctional relationships because ultimately they tend to give more than they receive. 

Echoists seem quite content in putting others' needs before their own and this is just as unhealthy, especially when taken to extremes. 

We see this a lot in many co-dependent and 'people-pleasing' relationships because the truth is where you find narcissism - echoism is always close-by. The irony is that as some people obsess over how NOT to be a narcissist, they are really also just exhibiting self-absorption. 

In my opinion the only way to overcome trauma-based personality traits is to constantly observe ourselves. To be deliberate about the way we wake up each day and how we go to sleep and everything that we do in between that time. 

The most important step to healing our trauma is to observe our thoughts because our thoughts really do control our lives. 

If necessary we must go and find some way to help ourselves to develop self-love and healthy relationships, but most importantly we have to find ways to address our traumas so that we do not continue to hurt ourselves and others, especially our children. 

I will love to see a society that recognizes that we are ALL completely damaged, and ii am yet to meet a person who has absolutely no trauma at all. 

It's completely ridiculous to hate on people that you consider to be narcissistic because that basically makes you one as well, even though you were traumatized by such a person.

In this particular case ii do not believe that the solution is in the problem.....the only solution to this problem and most of our people-problems is LOVE! 

As a collective-people we really need to learn how to "unlove hate" and realize that unloved people hate themselves. And then you have people who are not able to unlove the person that hurts them and they keep going back for more because they don't really love themselves. So this vicious circle is causing havoc in our world today. 

Collective trauma in any society is real and not just historical facts. Besides the issue of the ‘fatherless family’ ii do believe that societal trauma is the second greatest risk to public health in our world today. And sadly all trauma emerges from empty egos because all versions of hatred dwell in empty egos that lack the ability to self-heal.

No matter what has happened to us, it is each one of our duty to ourselves and to our communities and to future generations to heal our own trauma.

And it's important to realize that healing does not mean that the trauma never existed and believe it or not ii have had patients who once healed, missed their trauma so much because it felt weird and abnormal to the patient to not have the trauma anymore...like something was 'wrong'...and these types of emotions are perfectly normal as well and simply means that more healing is necessary. 

The best thing you can do is to find a way to actually embrace your trauma, and please believe me, ii do realize how ridiculously awkward and  uncomfortable this suggestion sounds! I am suggesting that we try to find a way to actually 'love' our trauma through acceptance so that we may reach that place where the trauma and pain no longer controls your emotions, your thoughts and ultimately your life. 

Love truly is the ONLY remedy for emotional pain and trauma because trauma blocks love and love heals trauma and ii highly recommend it because it transformed my own life! 

 

If you claim to be an empath 

The Fatherless Family and how the plant can help us to be better parents

 

In my opinion the most significant health crisis the world is facing right now is that of “Fatherlessness”.

As a major public health disaster I now believe that every social ill faced by our children in this world is also directly related to fatherlessness.

Statistics reveal that children from fatherless homes are more likely to be poor, more likely to get involved with drugs and alcohol, more likely to drop out of school, more likely to do crime and most importantly these children are also more likely to suffer with health and emotional problems throughout their lives. They are also more likely to become parents while still teenagers thus exasperating the fatherless societal syndrome we are seeing play out today.

Some of the main root reasons for the rise in the fatherless family in our world today are illiteracy, illegitimacy, homelessness, prison, military service, certain fertility procedures and suicide.

Let’s take a look at some of the real consequences of fatherlessness in our world today.

1.   Scarcity is the back door to trauma, addictions and poor health 

If you take a look at the statistics revealed in the US Census Bureau under ‘Children’s Living Arrangements and Characteristics’ you will learn that in America children living in female-headed families with no father, had a poverty rate of almost 50%.

This shows that children living in fatherless homes are 4 times more likely to be poor.

In South Africa an alarming 60% of our children do not live with their biological fathers.

2.   The Fatherless Family is the Gateway to Alcohol and Drug Abuse

 

In my opinion the number one reason why studies show that children from fatherless homes often engage in self-harming behavior and present with high levels of addiction and anti-social behavior is the sense of abandonment and lack of confidence that children experience. This type of trauma can follow a person for a lifetime.

When you walk the streets of Cape Town many young people will tell you how they found affection and encouragement from gangsters. They will tell you straight up that they turned to drugs and alcohol to numb the daily pain. 

In many communities worldwide this is an ongoing pattern that fuels intergenerational trauma and ultimately some form of dependency and even co-dependency.

On average the studies reveal that fatherless children are 70% more likely to take drugs and 76% more likely to do crime. These are the dramatic consequences of fatherless families and their impact on public health.

 

3.   Children living within fatherless families are also living with poor mental and physical health

 

A 2006 study (Hofferth, S.L) looked at 1977 children from age 3 upwards living with a resident father, and showed that these children had far fewer externalizing and internalizing behavioral problems than children living in fatherless families. This study also showed that fatherless children are twice as likely to commit suicide.

The effect of historical changes that led to the destruction of the nuclear family unit also led to a total disregard for the nature of the father-child relationship and the impact of this relationship on human development.

How we show up in life is largely dependent on our overall state of health.

4.   Research reveals that 71% of high school dropouts are fatherless

Children from fatherless families have a greater struggle academically and this results in illiteracy, poor thinking skills and poor decision making skills. According to this research fatherless children are less likely to achieve academic qualifications in adulthood.

5.   Fatherless children are more likely to engage in delinquency and the result is crime

Studies have been carried out to explore the relationship between family structure and the risk of violence in neighborhoods. The results showed that if the number of fathers is low, then there is an increase in teen violence in those neighborhoods.

These studies also show that teenagers who live in areas with higher levels of family integration commit less violence and crime.

In the Journal of Marriage Volume 67 pages 767 to 780 it is reported that children living with both biological parents were less likely to experience sexual assault or to witness other types of major violence in their families compared to children living in single-parent or stepfamilies.

6.   Teenage pregnancy and the impact of illegitimacy

In many poor countries today people are controlled by the social grant and especially the child grant. This has also resulted in many poor families encouraging pregnancy as a means of securing an income for the family.

A lot of impoverished people can only see social grants as a short term solution to their daily hunger that prevents most people from calculating the true costs of raising a child.

In many places today this is the only income they have and the pressure to fall pregnant weighs heavily on young people.

Today in America 1 in 3 children are living without their fathers and the statistics show that teenagers from fatherless families are far more likely to be sexually active compared to teens living with their fathers. (Hendricks CS et al, 2005)

In many communities today the reality is that the dysfunctional family unit has ultimately led to the destruction of the nuclear family

 It is no secret that father involvement makes a huge difference in the emotional lives of children.

In a study of 17 000 children born in the UK in 1958 and who were followed up with at ages 7, 11, 16,23 and 33 revealed that children with involved fathers have less emotional and behavioral difficulties in adolescence and that teenagers who felt close to their fathers go on to have more satisfactory adult marital relationships.

This study also revealed that girls who have a strong relationship with their fathers showed a lack of psychological distress in adult life.

It is ironic that so many families are fatherless due to so-called Cannabis crimes…..and yet I have seen how this plant can heal these families and the millions of fathers who are imprisoned within the system of sadness.

How can Cannabis help to overcome the emotional impact of a father’s absence?

Cannabis can help us to allow ourselves to grieve the pain of growing up without a father. The plant can also help to build our self-esteem by helping us to let go of any guilt that often exists, and most importantly the plant can offer forgiveness. All of these things contribute to having healthier relationships.

I would really like to see a society where we have more “stay-at-home dads” and more fathers who are prepared to mentor fatherless children.

A society that nurtures the idea that single fathers could also be full-time caregivers to their children.

An increasing number of mothers are using Cannabis to help them parent and I encourage fathers to do the exact same!

Women have been using Cannabis to be better mothers since forever because the plant makes them feel better and happier in their bodies and minds.

Calmness and patience are two benefits that are most commonly reported and many mothers report that using Cannabis helps them to get into the headspace where they can patiently help with their children’s homework and activities.

Cannabis calms the nervous system down and helps busy moms to slow down enough to spend quality time with their children in the evenings.

Through responsible adult consumption of the plant so many moms say that they are able to be ‘truly present’ with their children and this inspires creativity.

Managing the often difficult emotions that come with parenting like frustration is easily overcome when you invite Cannabis into your lives

In the same way as some people use alcohol to escape their reality, other people use Cannabis to be more involved in what they are doing and we see this filtering through to the parenting realm.

Even though in my country we have fought decades for the Cannabis for Private Use Bill, it is important to note that it is still a punishable crime to be caught smoking Cannabis or anything in front of a child. So even though most people’s grandmothers are now using Cannabis there is still a huge stigma attached.

One thing I really do not want to see is a society where Cannabis is used against a parent in child custody battles and divorce settlements. We already have had over 50 years of this situation and I have personally been to court many times to help prevent people losing their children because they consume the herb.

Parenting is about consciousness and Cannabis makes us very conscious. If nothing else, it cuts down on alcohol consumption and this is a major win in our society

Conscious parenting and co-parenting is when as adults we let go of our egos, needs, desires and attachments to strive for judgment-free caring of all aspects of our children’s lives with the aim of raising children who are in touch with their authentic selves.

This all adds up to a gentler, calmer and more peaceful style of parenting where parents find ways to truly ‘be’ with their children.

It is interesting that adult-use Cannabis laws have been linked with a decrease in foster care admissions

A study conducted at the University of Mississippi looked at foster care admission in American states before and after adult-use Cannabis was legalized. Bear in mind that recreational use is still not legal in the state of Mississippi.

This study conservatively confirmed that there was at least a 10% reduction in total foster care admissions since legalization. The study also found that admissions due to physical abuse and neglect also decreased after legalization.

This proves that Cannabis legalization definitely reduces many threats to child welfare

Cannabis is already famous for helping people with stress and anxiety and many parents report that the plant helps them to be better parents and co-parents. Cannabis can help parents to overcome sleepless nights as well as the general frustration associated with raising children.

Cannabis is all about human health and happiness and there is a lot of truth in the fact that happy parents raise happy children so I encourage parents to have a look at how the many benefits of the human companion plant can bring more health and happiness into your life.

 

 

 

CBD and corona virus symptoms in 2024

There is now no doubt that CBD (Cannabidiol) can assist us to overcome the "sars virus" that is responsible for the corona.

And as so-called new variants are developed each year, the plant is busy building confidence in the ever emerging power of CBD in the presence of tiny amounts of THC. 

New research reveals that CBD inhibits the expression of the Nucleocapsid (N) protein that is critical for SARS-CoV2 virus replication. And by binding as an agonist to the Cannabinoid receptors, CBD reduces inflammation and lung damage.

In a December 2022 paper authored by Dr Carolyn Shover, she highlights clinical research that proves that Cannabis use is associated with lower severity in patients hospitalized for corona. 

According to the National Institutes of Health, the potential for Cannabis to influence the course of the corona disease was already published 3 years before the outbreak. So even before the virus was released, it was known that CBD could inhibit the sars-cov2 viral infection. 

Cannabis is one of the most powerful antivirals on Earth and it is CBD that possesses the ability to destroy viruses like corona and even HIV as a known potent antiviral itself. 

But all of the plant Cannabinoids are required to be present to achieve this antiviral effect. For example It is known that CBG (Cannabigerol) is equally effective against the alpha and beta variants. So both CBD and CBG are equally effective against blocking cellular entry of the corona virus. 

Always ask for "Full Spectrum" medicine. 

Don't forget that Cannabis through the Endocannabinoid System (ECS) controls our hormone system

All viruses play havoc on the human hormone system by bringing about a number of physiological changes in the body that ultimately affect the immune response.

All of the medical benefits of Cannabis together with the potent antiviral and anti inflammatory effects proves that Cannabis Medicine is capable of reducing the severity of corona virus. 

My patients tell me that their doctors and oncologists are incredibly impressed with the results from consuming low dose CBD on a daily basis and they want to learn more about the medicinal properties of the human companion plant. 

420 Highlights!

This years 3rd Green Cup event at Wacky Woods is promising to be one of the best Canna events of the year! 

Plettenberg Bay Practice at Danki Pa Eco Estate, Rietvlei Road, Plettenberg Bay 

Patient Testimony 

For book sales please contact me on vee.bush@gmail.com 

 

The real risks of male infertility and how Cannabis sativa L can reverse the anti-androgen agenda

For more than 100 years now this world has been pushing the agenda that Cannabis causes male infertility. For the past 45 years I have without fail received weekly panic stricken messages from men requesting information on this government perceived threat. I’ve also been using Cannabis for that long to help people to conceive.

From my perspective men that consume Cannabis have been taking the blame for infertility problems while in reality based on my clinical observations and the science the greatest risk is in fact an under developed female Endocannabinoid System (ECS).

What are the risks of male infertility in modern society?

1.      1. A daily dose of Endocrine disruptors, neurotoxins and carcinogenic compounds

The earliest history of endocrine disruptors goes back to the American pig farmers in the 1920’s when they became concerned about low swine fertility.

As far as pesticides go they all contain hormone disruptors and it’s interesting to note that the Sumerians used sulphur compounds to controls pests 4500 years ago according to the tablets. Sulfates are known hormone disruptors and are now even found in bottled water,

About 3200 years ago the Chinese started using mercury and arsenic in their pest control efforts. Today we have pesticides known as’ glyphosate’ and ‘squamiquart’ that also contain toxic hormone disruptors that are also neurotoxic.  It is said that no one on Earth can escape pesticide poisoning, not even on the North Pole where it has been detected.

Heavy metals, also been around since before creation, also known to block hormone receptors and testosterone production.

2.      2. The modern lifestyle is literally destroying the future of humanity

Caffeine and sugar are known hormone disruptors but more than half the population is addicted to both!

Known disruptors of human and animal hormones include but definitely not limited to BPA’s (Bisphenol A found in all plastic products, windows, eyewear, resins, food cans, bottle tops, water supply), caffeine, peanut butter, alcohol, nicotine, cosmetics, laundry detergents, soap, intimate products, toothpaste, Vaseline/petroleum jelly, toys, carpets, sugar and especially sugar substitutes definitely cause hormonal imbalances.

Even some essential oils like tea tree and lavender contain compounds that can affect the sex hormones.

All pharmaceuticals, pesticides, plasticizers and processed foods, including their packaging contain endocrine disruptors including milk, meat, poultry, cheese, yogurt, yellow oils, grains like bread, oats, crackers, pasta, rice, soya beans and cereals,

All of these items and many more can lower testosterone by increasing the activity of an enzyme called Aromatase. This enzyme converts testosterone into estrogen in men.

Also, all of these hormone disruptors are also carcinogenic and are in my opinion the biggest cause of the radical increase in hormonal cancers we are seeing today like womb, prostrate, testicular and breast cancers.

So not only are these human-made toxins able to cause cancer and disrupt hormones they are also all neurotoxic meaning that they also destroy brain cells.

There is no shortage of scientific papers providing evidence that all of these substances and even substances still unknown to us result in reduced testosterone levels in the blood. 

What happens in the womb during pregnancy?

Even more concerning is the effect of endocrine disruptors on the unborn baby.

In Pallotti et al, scientists explored the potential dangers including the disruption of testosterone production and reproductive tract development.

Maternal exposure to endocrine disruptors is a great risk to the unborn male baby and to the future of humanity. Here is a potent quote from this paper that is quite alarming:

“Maternal exposure during fetal life offers the greatest risk to the developing organism: exposure in this phase is associated with disruption of testosterone production and reproductive tract development, as demonstrated by the in vivo and in vitro detection of multiple anti-androgenic EDCs in fetal life.”

This is the phase in which sex is determined, with differentiation of the reproductive tissues, a fundamental step for the future development and maintenance of reproductive function.

In the male fetus, these processes are dependent on the initiation and maintenance of androgen activity. This may be disrupted by EDCs at various levels, including AR antagonization and interference with the synthesis of steroid hormones Disruption of these processes may thus lead to a risk of damage to the reproductive tissues while the fetus is still in the womb, leading to malformations (hypospadias, cryptorchidism, testicular hypertrophy, reduced anogenital distance), impairment of future fertility (altered spermatogenesis, infertility) and/or even the appearance of testicular tumors.”

Dr Pallotti’s  2020 paper had 97 citations as evidence of the potential dangers of endocrine disruptors to testosterone production, and I am just going to share a few here today for those who wish to do their own research and I really do encourage this. [1-6]

So as you can see the very last thing you need to worry about is Cannabis causing male infertility when you have so many other risks of exposure from governments and corporations.

The main pathway for endocrine disruptors to enter the body is through food, breast milk and water. Small children and the developing fetus are far more likely to be affected by these dangerous chemicals than adults.

The issues surrounding so-called safe low-doses remains highly controversial especially in the face of all the evidence that endocrine disruptors are very UNSAFE not only for us but also for future generations that have not even been exposed yet!

What does the science say about Cannabis and male infertility?

We know that the ECS controls the Endocrine system, the hormone system, and we also know that like most hormones, Testosterone actually increases Endocannabinoid tone. [7-8]

But this is not all! Scientists have also realized that testosterone also plays a vital role in the production of Endocannabinoids in the male body and especially 2-AG that is the human version of CBD produced within the body. [9-13]

There are literally hundreds of journal papers on this topic that prove the vital role of the ECS in sperm production and regulation.

People need to know that Endocannabinoids and therefore Cannabis are actually responsible for the production of human sperm. [14]

This means that a man with an underdeveloped Endocannabinoid System (ECS) will struggle with infertility issues.

Men need Cannabis to supplement their ECS and their sperm production with the human companion plant

Not only does human sperm express EC receptors but Anandamide, 2-AG and other Endocannabinoids are also present in human sperm. So clearly Cannabis has a role to play in human reproduction! [15]

 

The science also proves that there is no difference in testosterone levels between users and non-users of Cannabis. Here is a quote from the paper written by Dr Thistle and team for the Andrology Journal. [16]

“…indicating that recency of use, and not duration or frequency, had the strongest relationship with testosterone levels.

Serum testosterone concentrations were higher in men with more recent marijuana use.”

This paper was very interesting because it was a Danish study on American men and the study involved 1577 men. This study revealed increased testosterone levels among Cannabis using men and especially in respect of recency testing.

And here is a very recent study by Dr Janaina da Silva that was published in the World Journal of Men’s Health in 2023.

I’m a huge fan of Dr Janaina’s work because she also has a passion for exploring heavy metal toxicity and I’d love to just share her bio with you as she is doing incredibly important research in the field of Cannabis Medicine.

“Actually, I am researching the impact of cannabinoids used for recreational and therapeutical purposes on the male reproductive biology of mice and humans. Also, I am investigating the mechanisms that heavy metals can lead to repro-toxicity. My current interests also involve: cancer biology and therapy, cardiovascular diseases.”

Here is the punch line from her brilliant scientific paper:

 “Results: The testosterone production and the spatial distribution of Leydig cells did not change upon CBD and/or THC exposure versus controls after 48 hours or 9 days. The overall tissue morphology of the cannabinoids-exposed testis explants was similar to their control upon 24 hours or 9 days of exposure, a finding confirmed by morphometric analyses on short-term cultures. In line, the number of apoptotic cells was not affected by either 48 hours or 9 days of cannabinoids treatment versus mock. Cannabinoids had no impact on the number of proliferating cells nor on mRNA expression of genes encoding proteins involved in sperm cell differentiation, meiosis, or Sertoli and Leydig functions after 24 hours exposure.

Conclusions: Altogether, these findings show an absence of acute direct effects of exposure to cannabis-derived cannabinoids THC and CBD on testicular testosterone production and sperm cells ex vivo. Further studies are warranted to explore an indirect impact of cannabinoids on testis functions through the hypothalamic-pituitary-testis axis, as well as the potential effects of long-term exposures.” [17]

Infertility in general is becoming a worldwide health problem and it’s affecting people’s mental health and happiness. It is one of the many massive lies that has been fed to humanity, that Cannabis lowers testosterone. Please do not be afraid to invite Cannabis into your lives and especially into your bedroom.

Endocannabinoid deficiency is real and people need to know how to heal themselves from all kinds of medical conditions and especially infertility.

The proof is irrefutable that even though Cannabis has been helping people to conceive for thousands of years, It turns out that Cannabis has no direct effect on the incidence and evolution of male infertility.

Please feel free to reach out to me if you or a loved one needs any help to nudge their Endocannabinoid System in the right direction.

CITATIONS

[1] (Pallotti F et al, 2020) “Mechanisms of Testicular Disruption from Exposure to Bisphenol A and Phtalates” Journal of Clinical Medicine Volume 9 Issue 2 page 471, 8 February 2020 PMCID PMC7074154 PMID: 32046352 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074154/

[2] (Kortenkamp A, 2020) “Which chemicals should be grouped together for mixture risk assessments of male reproductive disorders?” Journal of Molecular Cellular Endocrinology page Volume 1 Issue 499, https://pubmed.ncbi.nlm.nih.gov/31525431/

[3] (Gaudriault P et al, 2017) “Endocrine disruption in human fetal testis explants by individual and combined exposures to selectd pharmaceuticals, pesticides, and environmental pollutants.” Journal Environmental Health Perspective 2017 Volume 125 Issue 1 page 11, https://pubmed.ncbi.nlm.nih.gov/28796631/

[4] (Conley J.M. et al, 2018) “Mixed “Antiandrogenic” chemicals at low individual doses produce reproductive tract malformations in the male rate.” Journal Toxicology Science 2018 Volume 164 pages 166-178, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677127/

[5] (Howdeshell K.L. et al, 2007) “Cumulative effects of dibutyl phthalate and diethylhexyl phthalate on male rat reproductive tract development: Altered fetal steroid hormones and genes.” Journal Toxicology Science 2007 Volume 99 pages 190-202, https://pubmed.ncbi.nlm.nih.gov/17400582/#:~:text=In%20the%20fetal%20male%20rat,critical%20for%20gubernacular%20ligament%20development.

[6] (Howdeshell K.L. et al 2008) “Mechanisms of action of phthalate esters, individually and in combination, to induce abnormal reproductive development in male laboratory rats.” Journal Environmental Research 2008 Volume 108 pages 168-176, https://pubmed.ncbi.nlm.nih.gov/18949836/#:~:text=Mixtures%20of%20phthalate%20esters%20with,during%20sexual%20differentiation%20in%20utero.

[7] (Kristie Conde et al, 2017) “Testosterone Rapidly Augments Retrograde Endocannabinoid Signaling in Proopiomelanocortin Neurons to Suppress Glutamatergic Input from Steroidogenic Factor 1 Neurons via Upregulation of Diacylglycerol Lipase-α” Journal Neuroendocrinology Volume 105 Issue 4, 6 March 2017 PMCID PMC5839320 PMID 27871072 NIHMSID NIHMS852640 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839320/

[8] (Borgquist A et al, 2015) “The role of AMP-activated protein kinase in the androgenic potentiation of cannabinoid induced changes in energy homeostasis.” Journal Physiological Endocrinology Metabolism  Volume 308, 2015 https://pubmed.ncbi.nlm.nih.gov/25550281/

[9] (Marzo DI et al, 2001) “Leptin-regulated endocannabinoids are involved in maintaining food intake.” Journal Nature Volume 410 pages 822-825, 2001, https://pubmed.ncbi.nlm.nih.gov/11298451/#:~:text=Leptin%2Dregulated%20endocannabinoids%20are%20involved%20in%20maintaining%20food%20intake

[10] (Malcher-Lopes et al, 2006) “Opposing crosstalk between leptin and glucocorticoids rapidly modulates synaptic excitation via Endocannabinoid release.” Journal Neuroscience Volume 26 pages 6643-6650, https://pubmed.ncbi.nlm.nih.gov/16775153/

[11] (Kola B et al, 2008) “The orexigenic effect of Ghrelin is mediated through central activation of the endogenous cannabinoid system.” Journal PloS One Volume 3 page 1797, https://pubmed.ncbi.nlm.nih.gov/18335063/#:~:text=The%20orexigenic%20effect%20of%20ghrelin,of%20the%20endogenous%20cannabinoid%20system

[12] (Kirkham TC et al, 2002) “Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulaton of eating by 2-arachidonyl glycerol” British Journal of Pharmacology Volume 136 pages 550-557, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573386/#:~:text=Endocannabinoid%20levels%20were%20compared%20to,2%2DAG%20in%20the%20hypothalamus.

[13] (Yoshida T et al, 2006) “Localization of diacylglycerol lipase-α around postsynaptic spine suggests close proximity between production site of an endocannabinoid, 2-arachidonyl-glycerol, and presynaptic cannabinoid CB1 receptor”. Journal of Neuroscience and Journal of Fertility and Sterility, Volume 26 Issue 18 pages 4740-4751, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6674155/

[14] (Claudia Osycka-Salut et al, 2017) “Anandamide induces sperm release from oviductal epithelia through nitric oxide pathway in bovines” Journal PloS One Volume 7 Issue 2 12 February 2017 PMID 22363468 PMCID: MPC3281848

[15] (M Rossato et al 2005) “Human sperm express cannabinoid receptor Cb1, the activation of which inhibits motility, acrosome reaction, and mitochondrial function” Journal Clinical Endocrinology Volume 90 Issue 2 pages 984-91, February 2005 PMID 15562018 https://pubmed.ncbi.nlm.nih.gov/15562018/

[16 ] (Thistle et al, 2017) “Marijuana use and serum testosterone concentrations among U.S. males” Journal Andrology Volume 5 Issue 4 pages 732-738 PMID 28395129 PMCID PMC5660879 https://pubmed.ncbi.nlm.nih.gov/28395129/

[17] (da Silva J et al, 2023) “The Acute Exposure of Human Adult Testis Tissue to Cannabinoids THC and CBD Does Not Impact Testosterone Production Nor Germ Cell Lineage” World Journal of Men’s Health Volume 41 Issue 4 pages 928-939 PMID 37118951 PMCID: PMC10523127 https://pubmed.ncbi.nlm.nih.gov/37118951/